Lose weight with science.
Improve long-term health.

Doctor led digital weight loss and longevity clinic. Focus on markers that matter for a longer, healthier life.

Start here

Two-minute assessment

Patient · 12 months

Biomarkers improving

All trending healthy

Blood pressure−24
142 / 92118 / 76
HbA1c−1.1
6.4%5.3%
Cardiovascular risk−62%
HighLow
Weight−16 kg
98 kg82 kg
Metabolic age−11 yrs
5241
Lean musclepreserved
Maintained+1.2 kg

Reviewed monthly by your named XYO doctor

CQC regulatedUK doctorsMHRA compliantICO data protection

Why we're different

A doctor-led service, from start to finish.

XYO is built around continuity. We take time to understand your weight loss goals and how we can benefit your health in the long run. Our focus is to support your long-term health so you can be healthy and stay active for life.

We use weight loss treatments as an adjunct, not an end goal — and we focus on improving your health overall: metabolic, cardiovascular, hormonal, bone and muscle health, long term.

Cardiovascular health

Blood pressure, cholesterol and resting heart rate tracked alongside weight.

Metabolic health

HbA1c, fasting glucose and insulin sensitivity, not just the scale.

Bone & muscle

Strength and lean mass preserved through every kilogram lost.

Hormonal & cognitive

Sleep, energy and mood — markers of how you actually feel.

XYO vs the rest

A real clinic. Not a checkout.

Two thirds of people who lose weight on GLP-1 alone regain it within a year of stopping. We aim to be different — by building the habits and tracking the markers that make the change stick.

XYO Health

Other providers

Continuity of care

Same named doctor every appointment

Different prescriber each time, or none

Assessment

Doctor-led video consult

Online form reviewed in a queue

Focus

Long-term metabolic & cardiovascular health

Prescription fulfilled, then silence

Lifestyle support

Personalised nutrition, training and habit coaching

Generic PDF, if anything

After weight loss

Maintenance plan to keep the weight off

Most patients regain — up to 2/3 within a year of stopping

Markers tracked

HbA1c, BP, cholesterol, HRV, body composition

Weight only

Continuity of care

XYO Health

Same named doctor every appointment

Other providers

Different prescriber each time, or none

Assessment

XYO Health

Doctor-led video consult

Other providers

Online form reviewed in a queue

Focus

XYO Health

Long-term metabolic & cardiovascular health

Other providers

Prescription fulfilled, then silence

Lifestyle support

XYO Health

Personalised nutrition, training and habit coaching

Other providers

Generic PDF, if anything

After weight loss

XYO Health

Maintenance plan to keep the weight off

Other providers

Most patients regain — up to 2/3 within a year of stopping

Markers tracked

XYO Health

HbA1c, BP, cholesterol, HRV, body composition

Other providers

Weight only

The team behind XYO

Built by doctors who saw the gap first-hand.

XYO is led by UK-qualified doctors with deep experience in weight management, metabolic medicine and longevity — combining evidence-based prescribing with real, ongoing clinical care.

Dr Umair Mughal

Founder · UK-qualified doctor · Imperial College London

GMC registeredLongevity-focused

Dr Umair is a UK-qualified doctor who graduated from Imperial College London in 2017. In practice he saw the same pattern again and again — the toll excess weight takes on physical and mental health — and patients rarely given the tools to change it.

He founded XYO to close that gap, pairing an AI-powered coaching app with doctor-led care so people can build the lifestyle changes that actually drive results, with medication used carefully where it helps.

Dr Shiraz Deen

Partner · GP · Weight management & metabolic medicine

GMC registeredGLP-1 & GIP expertise

Dr Shiraz Deen is a GP with a special interest in weight management and metabolic medicine, with particular expertise in GLP-1 and GIP receptor agonist therapies — including semaglutide and tirzepatide.

He combines evidence-based prescribing with ongoing clinical monitoring and lifestyle support, helping patients achieve safe, sustainable results over the long term.

Who XYO is for

The right fit — and an honest look at when we're not.

XYO is for you if…

You want a doctor-led, longer-term approach to weight and metabolic health — not just a prescription
You're ready to engage with a personalised nutrition and exercise plan alongside any medication
You want continuity — the same named doctor tracking your progress over time, regular check-ins and direct support
You care about markers beyond the scale: HbA1c, cardiovascular risk, long-term metabolic health & longevity

May not be the right fit if…

You're looking for the fastest, cheapest route to a prescription with no or minimal clinical check-ins
You're not currently able to engage with lifestyle changes alongside treatment
You want a single transaction rather than an ongoing clinical relationship
You're only focused on the number on the scale today, not your health over the long run

How it works

Four steps from curious to cared for.

Step 01

Complete the questionnaire

A short online questionnaire about your health, history and goals.

Step 02

Get your options, side by side

We analyse your responses and present your package options — so you can compare clearly.

Step 03

Meet your named doctor

Once you choose your package, we allocate you a doctor who'll stay with you throughout.

Step 04

Start your transformation

Book your first call and begin your weight loss and longevity journey with full clinical support.

Patient stories

Real results, from real patients

A small selection of people we've worked with — long-term, not one-off.

"I've tried everything for years. Having a doctor who actually knows me and reviews my bloods every month changed it. Down 18kg and my HbA1c is back in range."

Sarah M.

Patient, 14 months

"What sold me was the continuity. Same doctor every call, not a new face each time. He spotted my thyroid was off before I'd even noticed symptoms."

James R.

Patient, 9 months

"The focus on long-term markers — not just the scale — is exactly what I wanted. My cardiovascular risk has more than halved."

Priya K.

Patient, 11 months

FAQs

Questions, answered.

Can't see what you're looking for? Your doctor will go through everything on your first call.

How is XYO different from other weight-loss services?+

You get a named UK-registered doctor who manages your care long-term — same doctor every call, monthly reviews of your bloods and markers, and direct support between calls. It's a real clinic relationship, not a checkout.

Who is XYO for?+

Adults who want sustainable weight loss alongside better long-term metabolic and cardiovascular health. We're a fit if you care about markers beyond the scale — HbA1c, lipids, blood pressure, longevity.

What does it cost?+

Pricing depends on the package and medication you and your doctor decide on together. You'll see clear options side-by-side after your questionnaire, before you commit to anything.

Do I need to come into a clinic?+

No. Everything — consultations, reviews, prescriptions, follow-ups — is handled remotely. Blood tests are done at-home or at a local partner lab.

Are the doctors UK-registered?+

Yes. Every clinician on XYO is GMC-registered and UK-based. You'll know your doctor by name from day one.

What if I'm not eligible?+

Medication isn't the only path. Your doctor can suggest tailored exercise, nutrition plans, and lifestyle or behavioural changes — there are always several ways to reach your health goals, and sometimes lifestyle changes alone do the job. That's exactly why a doctor-led approach matters: you get the right plan for you, not a default prescription.